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KMID : 0861120190230020091
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Korean Journal of Oriental Preventive Medicine
2019 Volume.23 No. 2 p.91 ~ p.99
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Reference value of serum amyloid P : a systematic review
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Park Sun-Ju
Jung Jee-Youn
Jang Soo-Bin
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Abstract
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Objectives : The aim of this study was to examine the reference value of biomarker serum amyloid p (SAP) to diagnose blood stasis objectively.
Methods : Pubmed-Medline, Cochrane library, EMBASE were searched using the key words ‘SAP’ and ‘serum amyloid p’ in June 2018. Original articles of human adults that published in English, studies that recruited from the clinical research settings or well defined population based cohorts were only included.
Results : A total of 12 studies were selected to extract the reference value of SAP. It was between 8.5 ng/mL (0.0085 mg/L) to 57.5 mg/L. Although the disease varied, most of them showed elevated SAP levels in the disease group (1.1-1.5 times).
Conclusions : This study is meaningful in that it summarizes the results of previous researches of SAP, which has the potential to be diagnostic index of blood stasis.
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KEYWORD
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serum amyloid P, SAP, blood stasis, biomarker, reference value, reference range
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